Thyroid Strategies for Endocrinologists-The Evaluation and Management of Hyperthyroidism in Pregnancy

Video Transcription

Video Summary

The video is a lecture on the evaluation and management of hyperthyroidism in pregnancy. The speaker, Dr. Chrysoula Dosu, discusses the prevalence and differential diagnosis of maternal hyperthyroidism, as well as the complications it can pose to both the mother and the fetus. She emphasizes the need to use pregnancy-specific reference ranges for thyroid hormone levels and the importance of monitoring thyroid-stimulating hormone receptor antibodies (TRAB) in the differential diagnosis. Dr. Dosu also presents data on the teratogenic effects of antithyroid drugs, such as methimazole and propylthiouracil, and suggests that PTU may be safer than methimazole in pregnancy. She discusses the role of surgery and radioactive iodine in the treatment of hyperthyroidism, and highlights the need to consider individual patient factors and risks in making treatment decisions. The lecture concludes with recommendations for the management of hyperthyroidism in pregnancy, including close monitoring of thyroid function and TRAB levels, and the consideration of withdrawal or dose reduction of antithyroid medication in stable patients during pregnancy.

Keywords

hyperthyroidism

pregnancy

evaluation

management

maternal hyperthyroidism

thyroid hormone levels

TRAB

antithyroid drugs

surgery

monitoring