MENA 2024 Recordings-Short Stature in Children

Video Transcription

Video Summary

The speaker discusses the evaluation of short stature in children, highlighting that short stature is one of the most common reasons for referrals to pediatric endocrinology clinics. They explain that most cases are due to familial short stature or constitutional delay of growth and puberty rather than organic disease. The discussion includes a detailed exploration of case studies, such as Karim's case of short stature and undiagnosed growth hormone deficiency due to a craniofaryngioma, highlighting the importance of clinical follow-up, re-evaluation, and thorough diagnostic processes. The speaker emphasizes the need for careful history taking, clinical examination, and appropriate use of diagnostic tests, like IGF-1, IGF-binding protein, and bone age, while considering variability in lab results. Additionally, the importance of accurate height measurements and the interpretation of growth velocity in context of age and pubertal status is discussed. Finally, genetic considerations in cases of idiopathic short stature are noted, along with FDA-approved therapies for growth hormone-related conditions, underlining a holistic, individualized approach to diagnosis and treatment.

Keywords

short stature

pediatric endocrinology

growth hormone deficiency

clinical evaluation

diagnostic tests

genetic considerations

individualized treatment