MENA 2024 Recordings-Differentiated Thyroid Cancer- Updated Guidelines

Video Transcription

Video Summary

The presentation provides an update on upcoming American Thyroid Association (ATA) guidelines for thyroid cancer, emphasizing a shift toward precision and personalized medicine. The current guidelines date back to 2015, but the new ones in 2025 will be more focused, divided into separate guidelines for thyroid nodular disease and thyroid cancer. The speaker highlights the pitfalls of overdiagnosis and overtreatment, presenting two patient cases to illustrate tailored treatment strategies. Past practices often resulted in near-total thyroidectomy and radioactive iodine treatment for all; however, new approaches may include less invasive procedures, and even active surveillance, particularly for low-risk cases.<br /><br />The presentation underscores the significance of a molecular understanding of thyroid cancer to improve individual prognostication and therapy strategies. The speaker notes advancements in molecular diagnostics that help identify risk more accurately, moving away from traditional blanket treatments. This also includes utilizing RNA-based prognostic tools similar to those in breast and prostate cancer.<br /><br />Lastly, the speaker mentions ongoing discussions about creating more fluid, "living" guideline documents due to rapidly evolving research and insights. They discuss emerging trends, such as single-cell analysis and metabolomics, that further personalize and advance thyroid cancer treatment.

Asset Subtitle

Dr. Erik Alexander

Keywords

ATA guidelines

thyroid cancer

precision medicine

molecular diagnostics

personalized treatment

active surveillance

living guidelines