Bone and Parathyroid Strategies for Endocrinologists-Parathyroid Disease: A 2022 Update

Video Transcription

Video Summary

The video recording of the Parathyroid Symposium features Dr. Jad Sfeir as the moderator. Dr. Alia Khan, who was unable to attend in person, had her presentation slides shared and presented by Dr. Sfeir. Dr. Khan focuses on providing updated guidelines for managing primary hyperparathyroidism. She discusses the diagnosis, emphasizing the importance of high serum calcium levels after accounting for albumin and elevated or normal parathyroid hormone (PTH) levels. Dr. Khan also explores imaging techniques for localization and the various clinical manifestations of primary hyperparathyroidism. Evaluating patients through biochemical testing and skeletal imaging is recommended. As for medical management options, Dr. Khan mentions bisphosphonates, denosumab, and cinacalcet. Indications for surgery and the potential complications of parathyroidectomy are also covered. Non-classical manifestations, such as neurocognitive symptoms and cardiovascular disease, are briefly addressed.<br /><br />Dr. Rob Wormers takes over and addresses the management of persistent and recurrent hyperparathyroidism. He emphasizes the importance of an experienced surgeon and discusses the risks and benefits of additional surgeries as well as different localization strategies. The use of intraoperative parathyroid hormone monitoring and the management of non-surgical candidates are also discussed, with case examples provided. A question and answer session concludes the video.<br /><br />The video also touches upon hypoparathyroidism, stressing the difficulty in distinguishing it from primary hyperparathyroidism based solely on biochemistries. The prevalence of primary hyperparathyroidism is highlighted compared to hypoparathyroidism. Genetic causes of hypoparathyroidism, including autoimmune and familial factors, are mentioned. Management typically involves calcium and vitamin D supplementation to maintain normal or slightly elevated serum calcium levels. Potential complications, such as high bone density and basal ganglia calcification, are discussed, along with guidelines for management and monitoring.<br /><br />In summary, the video provides an extensive overview of primary hyperparathyroidism and touches briefly on hypoparathyroidism, discussing their diagnosis, management options, complications, and guidelines.

Keywords

Parathyroid Symposium

primary hyperparathyroidism

diagnosis

serum calcium levels

parathyroid hormone

imaging techniques

medical management

surgery

complications

hypoparathyroidism

calcium supplementation