Bone and Parathyroid Strategies for Endocrinologists-Osteoporosis Conundrums

Video Transcription

Video Summary

The video discusses various topics related to bone health, including transplant-related bone disorders, bone health in transgender individuals, and the use of bone turnover markers in clinical practice. Dr. Gigi Abate presents on the high risk of osteoporosis and fractures in pre and post organ transplant patients, focusing on liver transplant recipients. She recommends using bone density scans and x-rays to assess fracture risk and highlights bisphosphonates as the main treatment option. Dr. Vin Tengpreetcha discusses bone health in transgender individuals, stating that transgender women have lower bone density prior to hormone therapy but experience improvements after starting treatment. Transgender men have neutral or slightly improved bone density and lower fracture rates compared to cisgender men and women. Dr. Albert Hsieh discusses bone turnover markers and their use in clinical practice. He explains the bone remodeling cycle and mentions serum CTX and P1NP as commonly used markers. He acknowledges the limitations of using these markers, such as variability and limited evidence. Dr. Hsieh presents two clinical scenarios where bone turnover markers have been studied: assessing treatment response in osteoporosis and monitoring bone health in glucocorticoid-induced osteoporosis. The video concludes with a Q&A session. Overall, the video provides insights into various aspects of bone health, including specific populations at risk and the utility of bone turnover markers in clinical management.

Keywords

bone health

transplant-related bone disorders

transgender individuals

bone turnover markers

osteoporosis

fractures

organ transplant patients

bone density scans

bisphosphonates

hormone therapy

glucocorticoid-induced osteoporosis