Adrenal, Pituitary, Gonad, and Neuroendocrine Strategies for Primary Care-Disease State Network Year-in-Review-PGAN

Video Transcription

Video Summary

In this video summary, several studies in the field of pituitary, gonadal, adrenal, and neuroendocrine tumors are discussed. The first study focuses on the use of plasma steroid profiling to distinguish different types of adrenal tumors. Researchers found that combining plasma steroid profiling with metanephrines and adrenal lesion size can help identify the type of adrenal tumor with high accuracy. The second study examines the use of ACTH stimulation during adrenal venous sampling and its impact on lateralization. The study found that ACTH stimulation can underestimate surgically curable primary aldosterone. The third study investigates the relationship between acromegaly and the risk of developing non-pituitary tumors. The study found that acromegaly patients have an increased risk of certain cancers, including colorectal, anal, kidney, and ureter malignancies. The fourth study looks at the effectiveness of oral octreotide in the treatment of acromegaly. The study found that oral octreotide was non-inferior to injectable somatostatin receptor ligands in controlling IGF-1 levels. The fifth study focuses on the use of ocilodrostat in the treatment of Cushing's disease. The study found that ocilodrostat effectively normalized urinary free cortisol levels in patients with Cushing's disease. Overall, these studies provide valuable insights into the diagnosis and treatment of pituitary, gonadal, adrenal, and neuroendocrine tumors.

Keywords

pituitary tumors

gonadal tumors

adrenal tumors

neuroendocrine tumors

plasma steroid profiling

ACTH stimulation

acromegaly

oral octreotide

Cushing's disease