Adrenal, Pituitary, Gonad, and Neuroendocrine Strategies for Endocrinologists-Disease State Network Year-in-Review-PGAN

Video Transcription

Video Summary

In the video, Diane Donegan from Indiana University presents a year in review for pituitary, gonadal, adrenal, and neuroendocrine tumors. She discusses the expansion of educational opportunities for these conditions, including a disease state network blog, podcasts, and white papers. <br /><br />One study discussed in the video focuses on mortality trends in transgender individuals receiving hormone treatment. The study found a 2-fold increase in mortality risk compared to the general population, with cardiovascular disease being the most common cause of death among transgender women. The study highlights the importance of monitoring and treating comorbidities in transgender individuals.<br /><br />Another study examines the utility of plasma steroid profiling in discerning adrenal tumor types. The study found that a combination of plasma steroid profiling, plasma metanephrines, and adrenal lesion size can help identify different adrenal tumors.<br /><br />In acromegaly, one study looked at the predictors of tumor shrinkage in patients with prolactin-secreting tumors. The study found that the degree of tumor shrinkage at three months post-treatment predicted tumor shrinkage at 12 months.<br /><br />Another study in acromegaly explored the incidence of non-pituitary tumors in acromegaly patients. The study found an increased incidence of colorectal and anal malignancies, kidney and ureter malignancies, and benign tumors in acromegaly patients compared to the general population.<br /><br />The video also discusses the progress in medications for pituitary conditions, including the approval of oral octreotide for acromegaly and the use of steroidogenesis inhibitors for Cushing's disease.<br /><br />These studies highlight the advances and challenges in the field of pituitary, gonadal, adrenal, and neuroendocrine tumors, and the importance of personalized care and monitoring for these conditions.

Keywords

pituitary tumors

gonadal tumors

adrenal tumors

transgender individuals

mortality trends

plasma steroid profiling

acromegaly

tumor shrinkage

medications