ASAP Live Session: Reproductive Disorders - Thursday, August 17, 2023: 7:00-8:00 pm ET-Slides

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A study conducted in the United States, published in May 2021, has found that low testosterone levels in men are associated with an increased risk of severe COVID-19 infection. The study, which involved more than 200 male patients hospitalized with COVID-19, found that those with low testosterone levels were more likely to require intensive care, need mechanical ventilation, and have a longer hospital stay compared to those with normal testosterone levels. This association remained even after adjusting for age, obesity, and underlying health conditions. The findings suggest that testosterone levels may serve as a biomarker for COVID-19 severity in men and that testosterone replacement therapy could potentially improve outcomes in these patients. However, further research is needed to confirm these findings and explore the underlying mechanisms. The study adds to the growing body of evidence linking sex hormones to COVID-19 outcomes, with previous studies showing that estrogen, progesterone, and androgens may influence the immune response to the virus. Understanding the role of hormones in COVID-19 could help identify individuals at higher risk and guide targeted interventions to improve outcomes.

Keywords

United States

study

low testosterone levels

men

severe COVID-19 infection

intensive care

mechanical ventilation

biomarker

testosterone replacement therapy

COVID-19 severity