ASAP Live - Diabetes 1-Diabetes 1 Slides

Diabetes 1 Slides
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Summary:<br /><br />This document provides information on various cases related to diabetes and hypoglycemia. Each case presents a patient scenario and asks a question related to the management or diagnosis of the condition. The document also includes explanations and rationales for each case.<br /><br />In Case 1, a 67-year-old woman with diabetes type 2 and congestive heart failure is being evaluated for management. The best next step for this patient is to discontinue glipizide and replace it with a sodium-glucose cotransporter 2 inhibitor (SGLT2i) to reduce the risk of heart failure and cardiovascular death.<br /><br />Case 2 involves a 35-year-old man with type 1 diabetes who is experiencing hypoglycemia. The best next step for this patient is to substitute his basal insulin with degludec to decrease the incidence of nocturnal hypoglycemia.<br /><br />Case 3 features a 39-year-old woman with dizziness and a history of Roux-en-Y gastric bypass surgery. The most likely diagnosis for this patient is nesidioblastosis, a condition characterized by postprandial hyperinsulinemic hypoglycemia.<br /><br />Case 4 presents a 48-year-old man with abnormal blood test results and a family history of diabetes. The best next step in management for this patient is to start lifestyle interventions and metformin therapy.<br /><br />In Case 5, a patient with type 2 diabetes is advised to add a weekly injection of a glucagonlike peptide-1 (GLP-1) receptor agonist to his treatment regimen. The correct explanation for how the GLP-1 receptor agonist improves glycemic control is that it stimulates glucose-dependent insulin release.<br /><br />Case 6 involves a woman with type 1 diabetes who is experiencing worsening glucose control and insulin resistance. She has insulin therapy-related lipoatrophy, which is an immune-mediated inflammatory response to insulin.<br /><br />In Case 7, a patient with type 2 diabetes is admitted to the intensive care unit with septic shock. The expected outcome of maintaining a glycemic target of less than 200 mg/dL is a reduction in overall mortality.<br /><br />Overall, the document provides insights into the management and diagnosis of diabetes and hypoglycemia in various patient scenarios.
Keywords
diabetes
hypoglycemia
patient scenarios
management
diagnosis
glipizide
SGLT2i
basal insulin
degludec
nesidioblastosis