AACE Rare Endocrine Disease Series On Demand: Are these Changes in my Health Significant? Identifying and Treating Cushing’s Syndrome-AACE Rare Endocrine Disease Series On Demand: Are these Changes in my Health Significant? Identifying and Treating Cushing’s Syndrome

AACE Rare Endocrine Disease Series On Demand: Are these Changes in my Health Significant? Identifying and Treating Cushing’s Syndrome

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Video Transcription

Video Summary

In the webinar on Cushing's Syndrome, experts including Dr. Ricardo Correa, Dr. Shobhana Atimulan, and Chris Jedinak addressed key aspects of the condition, from diagnosis to management and complication handling. Dr. Correa initiated the session outlining the diagnosis strategies for Cushing's Syndrome, noting that it is also referred to as hypercortisolism. He detailed the importance of differentiating between ACTH-dependent and ACTH-independent causes through various tests like late-night salivary cortisol and the dexamethasone suppression test. Dr. Atimulan then explored treatment options, emphasizing that surgery is primary, except in cases where it is not feasible. She discussed medical therapies, comparing options like ketoconazole and mifepristone, and provided insights into managing glucocorticoid withdrawal syndrome. She used case studies to illustrate the real-world implications of treatment, underscoring the challenges in choosing the right therapy based on the patient's condition and comorbidities. Finally, Chris Jedinak highlighted the comorbidities associated with Cushing's, such as cardiovascular and metabolic issues, and stressed the necessity of long-term management strategies to address persistent risks like thrombotic events and osteoporosis. The webinar concluded with a Q&A session, where experts addressed audience inquiries about combining therapies and prophylaxis for specific complications. This comprehensive discussion provided attendees with a holistic view of Cushing's Syndrome, from diagnosis through long-term management of complications.

Keywords

Cushing's Syndrome

hypercortisolism

diagnosis strategies

ACTH-dependent

ACTH-independent

treatment options

glucocorticoid withdrawal

comorbidities

long-term management

thrombotic events