AACE MENA 2025-Osteoporosis in Men

Video Transcription

Video Summary

Dr. Nadeem discussed osteoporosis in men, highlighting key differences from women. Men achieve higher peak bone mass in their 20s and experience bone loss later, around age 50, but despite this, men have higher mortality and worse outcomes after fractures. Fractures in men tend to occur about a decade later than in women but carry greater morbidity and mortality. Screening for osteoporosis in men is less common due to lack of formal recommendations and limited data, leading to underdiagnosis and undertreatment. Most treatment efficacy studies in men focus on bone density rather than fracture reduction, with fewer men included and limited fracture endpoint data. However, recent studies show that screening and treatment in men improve bone density and reduce fracture risk similarly to women. European guidelines support using female data for diagnosis and treatment thresholds in men. Vertebral fractures are common in older men, often occurring even with normal bone density. Improved awareness, screening, and treatment adherence are critical to reducing osteoporosis-related morbidity and mortality in men.

Keywords

osteoporosis in men

bone mass peak age

fracture morbidity and mortality

osteoporosis screening challenges

treatment efficacy in men

European guidelines on osteoporosis