#AACE2021: Top 20-Advances in the Management of Thyroid Cancer

Video Transcription

Video Summary

In this video session titled "Advances in the Management of Thyroid Cancer," moderated by Sina Jassim, three doctors - Dr. Naifa Boussaidi, Dr. Mike Tuttle, and Dr. Shelby Holt - discuss various aspects of thyroid cancer management. Dr. Boussaidi emphasizes individualized therapy for patients with papillary thyroid cancer and highlights the role of surgery as the primary treatment. Dr. Tuttle discusses advances in systemic therapies, such as targeted therapies like BRAF and RET inhibitors, and the importance of considering patient and tumor factors in treatment decisions. Dr. Holt focuses on thyroid cancer surgeries and their effectiveness.<br /><br />The session also delves into the concept of active surveillance for low-risk papillary thyroid cancer. This approach involves monitoring the tumor instead of immediate surgery, with regular ultrasounds and follow-up appointments. The speaker emphasizes that active surveillance is an active observation strategy, not a passive choice.<br /><br />Additionally, the video touches on the use of external beam radiation in the treatment of thyroid cancer recurrence, particularly in cases with poorly differentiated and tall cell variants. The speaker notes the conservative and targeted use of radiation in the adjuvant setting based on individual case considerations.<br /><br />The session briefly discusses the use of cell-free DNA analysis as an alternative to tissue biopsy for detecting and monitoring thyroid cancer. Specifically, it can provide information about tumor burden and progression by identifying specific mutations in cell-free DNA.<br /><br />Overall, the video provides insights into the advances in thyroid cancer management, including individualized therapy approaches, active surveillance, targeted systemic therapies, the use of external beam radiation, and the utility of cell-free DNA analysis.

Asset Subtitle

Shelby Holt, MD | Naifa Busaidy, MD, FACP, FACE | Michael Tuttle, MD | Sina Jasim, MD, MPH

Keywords

Thyroid cancer management

Individualized therapy

Surgery as primary treatment

Systemic therapies

BRAF and RET inhibitors

Thyroid cancer surgeries

Active surveillance

Ultrasounds and follow-up

External beam radiation

Poorly differentiated variants

Cell-free DNA analysis

Tumor burden and progression

Specific mutations